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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6c351a6b63ed9994202215ac9606bb1a18d3c9cce4f4eec1fe59450268e2ec5' 
  AND token = 'iB0jPsS+OyCtlX1L3XzJMlyMyJqy1xNxfauISVIVXxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}