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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd7ad9f83e593d16cc63b9faf36eb90751eec1ec42b2d2f0e545e83684682d06' 
  AND token = 'Jw8g1GyTLszNK8sUdO2aiR3GHsBJ5EMRelMGm0WQCuo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}