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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '156f21193c920592438cf3ccf974eb93fba06de40fead77bbd39ac7c0eeb4ff4' 
  AND token = 'jtdyJjalmRs4RuFzuk1OWyHjvO7nG7IYH2ldbB0hbeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}