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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8473fbc0e2266def22220a238d857e28d59678041d17cd72525505d341f43b84' 
  AND token = 'Z0qy+b6qRv+aP9exUtY+eAtqBX6y7zQC1YwfkLhzIfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}