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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ea9124eeec8cda76d1c0aaddc8196fb0489e619e302f48f0dae3d2ac270c549' 
  AND token = 'hHVrg26zLNFwIw48vFG+sQuN2Qhmo9tR+3OQe5GT6ME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}