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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0874d7293c0654c4bd1c77f3495cee26b267633428a8c03038dea96f08013215' 
  AND token = 'k8HJpFJlq4B/UCfcPo2OD3j8I7xYcJRbjX7zy6Z++N4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}