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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27eed79330408a37a414f72aac84f1a68adc0aeb30099b5e2dafe8fcc7d9dde4' 
  AND token = '8fQ+u8wEnrF1BI1F+7gaGKzSCPFLypTRGoPxQyMSpgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}