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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8dc925e6e429e4a9fbec039f4ea653c0c3521f6afffd0b5aa38bb3f8893628de' 
  AND token = '4OsHVEKGEUyhJqpcCFworo6u7PQU1hDSEFDqvOcEG9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}