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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a471bd2019d2ff87503290dcbb00f23591ea7da54126146725d170be1a3aeb68' 
  AND token = '6XyUgS2c3X5pFIIgtt8nAHc+80zmbLyg6RjsAJBfHB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}