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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cf8deba44f9025544fa0ac662d59055ce494cd94b28f8e181b2cd47ecb7f9d0' 
  AND token = 'SyyKYgj8KGxSYZ5uNG+/npIkIv22WkO1+28G01wZUy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}