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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86f09c91ef4857b1feb1ad35453df92c2f55fee6fb863123084ced185a06f764' 
  AND token = 'WgVe2P0GI5cr4vc20UpPhUbsazXKR1zkASDIT31QkXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}