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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10d260b6fbbb35610b5465afddb99e1fc0379f3ebe4adde7281aadf57b34370c' 
  AND token = 'JR7nSqu56Su5rrTlB45VsTAcT7j+O3gW+kjBvFelD6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}