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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8def9ef76a08e6cc1336a9f0ac3c2c98f514977e1483d3e2d8504470c5226eb1' 
  AND token = 'UjADvzfel1WkYZOBfCDSPczDuIchdwofxizq6CD4k0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}