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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e64573435e6aaab57744c9db65a40cfe24be0156e48abd90b12e5f165aa881c3' 
  AND token = 'Y+Vam1ClnSwoZZjJGxk0tRgpWPpnJj4ceDGsDTL5s18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}