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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e42dc85986959c6f1b99724c57cdfc5d0c212d432cb4f95860a9b6009559b356' 
  AND token = 'sag9GqEGUr/RmsabLXVxRYoZ1GUX+wCggbMKxyycyCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}