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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e3c9b73cb73504288d34b166f8b2d3bdf28ea32eadae42006827df06573c649' 
  AND token = 'kcUZCdBIkIp0kigTMpq+f158IIopXoKaBgvVK64l78Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}