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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e45d0f6780ff62586bde3f470655b421799f9b5517bf0e4d01d7612de6c8afe' 
  AND token = 'PVSc3Yz8MY86PzfP2j04MEmVb8WlCyzD8xzEzVQ+WfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}