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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3b232299f4636011c3399cb05f8f0db8066ffc3b1634962e1af4d7aec6e6ad5' 
  AND token = 'sMNOXvXqigdhOIQZ/Rg10J1Ap2venoCE8BUBb6JZFWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}