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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9128a7cec27fd235582cc9f416d16b6ec3964abe249e17d116eaa7d960e053a' 
  AND token = 'nQG4yM+Os7eeRJVmAlBWzrh1RRruKdLk4IfY/QGVuG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}