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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66798ddc48b79a8f6989f108f803fb16b3aa0802a8353d3c75028bfb41d9e894' 
  AND token = 'tkNL6T49g5lie8cz9WN5+AEtWZtLizYLeasBTXmY8so=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}