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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f72a9c6e48a9c3ee44bfcef26c40d9a2c838883d2308830ddc417de8c8568e2d' 
  AND token = 'xh+hY6xs2zpJdiV7x3CpLeLSeOegQp9rZrmKSHWXmVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}