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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a8fa1cb29e2475fc584b46c526ac5c7cfe145ebdfbca35e778fa97070ba8280' 
  AND token = 'ieqn50EMQV4n/YiGzGAT35OJtLj+gqA5vwZSNp1yyOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}