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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd49aa07dcb08c99a1c8560c5bd8aeb9f2a0057029f076d7263b52be2280c50bb' 
  AND token = '1TeA5fGKJmfMPhqM8/XXnDsyXyz8uGZ0EcfsUz1S30U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}