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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '801f61fda1819c92f1b8060cd7e8b5b4fce64106e08af6d74863dbf419e1b5af' 
  AND token = '8TRVxdPGlP5HVnfO64uv3LqcHSjj31EQZbwfvmD/PRg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}