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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2174fe016d43f6743588aec29309cec0ef9f60e30ded02343fbc251ecd79d4b6' 
  AND token = 'aWFTRnzvNwpF22VBz/uY1S/MyBfYnynpwvGpzwwSiBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}