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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6a0adc4a28f480f3281e107ea8520db0dee9788321f31e2e9dec29c2fd34ae4' 
  AND token = 'U4iOGD5yKx5oKJJ8JHb9k4RBiauR3AMP9608GIUn7Bw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}