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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a4ffe89aadea88fa82eb57db1661a9fdb595104f7ad2f10b9d44f86744c0ca0' 
  AND token = 'veJc9Uu1Nn6zxb4kFHGuQGxyOUJIFLbh9FHvrTr8gt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}