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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c06457bca9cd5f66cc66042ebf00a5d0a1c60106c9786080f0c5e7d80f69016' 
  AND token = '09o7vq6YcNU14sVpkR5pAhj+P+kValwaYQrY23XfIQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}