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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd01254563b745c79cef4279c14a84995ba9fed39082b63373c803ca8354d920d' 
  AND token = 'KnYuu08O6HJJJxSduohxK7dkupxPGb5pRRKFzUIzRZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}