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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29659e75afa8209a29886ea04cd9aa86a0b77c03c61d772c3ddafe01d0d4be4b' 
  AND token = '3G9gGuRfEX1QFYm37i8wumm61bRn3LQ9323NqfXTI+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}