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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48da5a3436e534d2025dd0ff07d9bdd5cf1dc61664d19f4f9fb107da2af2bc76' 
  AND token = 'wg2DjxM99TPmCmVlUuoD4pm9ZJ0rZ/GJUFkT3Sa5AXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}