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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8e296e39e7a011ee001ae6c367c78a2603e6734216e7cc786f772de9a1e8949' 
  AND token = 'JpPDGEafTlaox4PVHh3UVpqzfbUjREj6O+DYhfjrTAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}