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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fc783ae53f6e933abd7e388c6e5307d730dd18af45a7dc7384be8438d311fd9' 
  AND token = '5mV4SOPQi78FmhXfWj2VxF5/Qqpm4dGg4c2rTrD/Msw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}