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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '274bf9396d7f9c1f329df8ba10a6b4080c5f4bde9fb47a28ac830eb397444b36' 
  AND token = 'HnlO6b0MjK2Iv9LrtLsADCG8T9xsLSb9NRK7NH5ce0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}