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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e2d8ce71a5750abdbfb65907e71f6df4af7b0789cda6630c77f549f8f485a38' 
  AND token = 'DzRrkxRHVRKWD3ywWZDN7zgH5qFxNcCEd8kWnRHwitI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}