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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '336107d58588ea6f214175a47534171c847905a889465b0637a33208dc97df45' 
  AND token = 'i5+DAW9RIyPllSX/DF2pCD34QqSc7eVV0YBjWOns93Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}