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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '408fbc991f56d745443bf26409abc2ca0974484fdd665b2388070888ab48c392' 
  AND token = 'ec+ONMukXe3XhdPk5Fx23aN9VTHqafK5/ozkBBk16Wg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}