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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf68e33c45b21bde929ea5ba7d5c16726e49bdc4b2df62d94176c231c57d78ac' 
  AND token = '1jMYHC1LFE6XOA2OOhCNSwbAV7jYWr2kB0BCiaAgTjY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}