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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9499ae029971ea30969f9cbff033c024d939a8fdc1a307aad1265b729c565746' 
  AND token = '2iZ9FPPy9Dk+v7UKI2fNM1BCHFEwbQB0dq+VD06YXVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}