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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b115a8252cbce71ded4d643ddbe8908c8d4d97ca8eeca6ee63a1883f816c8efc' 
  AND token = 'UBqZdoLw5XQXk9C4WSxlBr0KM1Sjw+xIuhdBKOQjYzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}