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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c363288c4b9c3d72e0b2b5ac1c002a97d22a390d1f54ed670b078b62f6101339' 
  AND token = 'Wz15zRc99LIJRNA9eLQr7STldJrA5abvYhginFxgZOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}