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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa0062ca991ee83e24d6ca7089cb142b1feb906364e336fa07b0a99dde0a12ed' 
  AND token = 'm/rmxusMF5EEaidBtOe99N5eWtRjxjaNqMiyIO7PR+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}