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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef8cb8ea1ff1222171ba52b7a429f9a02a76f0c6db9246611e174ce41fd001a6' 
  AND token = '43bolJyPpsymrWh5nJSuBiN93yP8E/G3xpN3lNfkFdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}