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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd883304680cf0b8a3e401f16b261ef8e53d6952f5ef28d000314f62be640a17c' 
  AND token = 'NX3zGEmBL/NSHy8ZKCM8bvtCSJA2sin0XvPt3oYdnjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}