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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4260587d93d702657ff9b285d205fc19a04ca73df2f3139352ff7f1ac141d2cb' 
  AND token = 'MLUuPxC9quhW/RcCqlwMrtj3g54QW7X9Re0dURvEuWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}