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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40267509f31376c254a4d9b70a6cf9208a9a44f5f6351c526ffb77e49e0f4ff5' 
  AND token = 'I96SReSPBxLMajmt8HamBmH+qLMFpU5iwuq45BjmL2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}