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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e246b097a20a28ec2c3ae4f0db9c1acc8e79a39c03a1945fb7a64a26fce23d35' 
  AND token = 'K1qw1PDkp0PermDMVHyRNcCwTO8Sxwp/5oSJlD54G5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}