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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b29ec345d8957b469c6b0b27c9108f97398c32ce759a5cff9587341a142435d7' 
  AND token = '7jj2toFW0k8zi1vZTDDL5msdEY+PMLglYP+lsVV0OEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}