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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3faab9d1d1aee4ad6f5185cf14012d4a1ee1d77d33385b5b8ee39a4dd65393a7' 
  AND token = '/yNRdiDM8L1cS5Z9Wv8c4n/gRlWIXCGdijMYtyqKldE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}