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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2baeaf27ea5d1dc37a6736f9b4d528f068b5dd96abb9ced6d7ac1934c38e0eef' 
  AND token = 'DFNNUfaLDCL5UEgks8K6g57z465tkT6kiAU88YJ9tIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}